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Introduction
PROZAC is one of the world's most widely prescribed antidepressants; it has been prescribed for more than 40 million people worldwide. Chances are, someone you know is getting better because of it.
PROZAC was the first of a new class of drugs, called selective serotonin reuptake inhibitors (SSRIs), to be approved for use in the United States. This new type of medication helps patients with depression by increasing the availability of serotonin in the brain. Scientists believe serotonin affects many types of activity in the brain, including the regulation of mood.
PROZAC was initially approved for treatment of depression in Belgium in 1986 and in the United States in 1987. Since then, it has been approved and marketed in more than 90 countries and prescribed for more than 40 million people worldwide.
The safety and effectiveness of PROZAC have been thoroughly studied in clinical trials with more than 11,000 patients. There have been more than 3,500 publications on PROZAC in medical/scientific journals.
How does PROZAC work?
Depression is not fully understood, but a growing amount of evidence supports the view that people with depression have an imbalance of the brain's neurotransmitters, the chemicals that allow nerve cells in the brain to communicate with each other. Many scientists believe that an imbalance in serotonin, one of these neurotransmitters, may be an important factor in the development and severity of depression.
PROZAC may help to correct this imbalance by increasing the brain's own supply of serotonin.
Some other antidepressant medicines appear to affect several neurotransmitters in addition to serotonin. PROZAC selectively affects only serotonin.
While PROZAC cannot be said to "cure" depression, it does help to control the symptoms of depression, allowing many people with depression to feel better and return to normal functioning. [ See graphics below ]
Below you will find animations of the serotonin system within the brain.
PROZAC is one of the world's most widely prescribed antidepressants; it has been prescribed for more than 40 million people worldwide. Chances are, someone you know is getting better because of it.
PROZAC was the first of a new class of drugs, called selective serotonin reuptake inhibitors (SSRIs), to be approved for use in the United States. This new type of medication helps patients with depression by increasing the availability of serotonin in the brain. Scientists believe serotonin affects many types of activity in the brain, including the regulation of mood.
PROZAC was initially approved for treatment of depression in Belgium in 1986 and in the United States in 1987. Since then, it has been approved and marketed in more than 90 countries and prescribed for more than 40 million people worldwide.
The safety and effectiveness of PROZAC have been thoroughly studied in clinical trials with more than 11,000 patients. There have been more than 3,500 publications on PROZAC in medical/scientific journals.
How does PROZAC work?
Depression is not fully understood, but a growing amount of evidence supports the view that people with depression have an imbalance of the brain's neurotransmitters, the chemicals that allow nerve cells in the brain to communicate with each other. Many scientists believe that an imbalance in serotonin, one of these neurotransmitters, may be an important factor in the development and severity of depression.
PROZAC may help to correct this imbalance by increasing the brain's own supply of serotonin.
Some other antidepressant medicines appear to affect several neurotransmitters in addition to serotonin. PROZAC selectively affects only serotonin.
While PROZAC cannot be said to "cure" depression, it does help to control the symptoms of depression, allowing many people with depression to feel better and return to normal functioning. [ See graphics below ]
Below you will find animations of the serotonin system within the brain.
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Normal serotonine system
This is a representation of the serotonin system. Serotonin is released into the space between the "sending" nerve cell and the "receiving" nerve cell. When serotonin is received on the surface of the "receiving" cell, it stimulates or activates serotonin receptors. Stimulation of these receptors generates an impulse and allows message to move forward. |
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In Depression:
When a person suffers from depression, there may be a problem with the balance of the serotonin system. |
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With PROZAC:
Many scientists believe that Prozac works by blocking the action of the serotonin uptake pump. When serotonin is released from the "sending" nerve cell, some of it is reabsorbed by an uptake pump. By blocking the serotonin uptake pump, Prozac increases the amount of active serotonin that can be delivered to the "receiving" nerve cell. This may help message transmission return to normal. |
Dosage
Doses are 10mg each, two per one 20mg pill. Typical dosage is 10mg (half of a pill) twice a day.
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